I have been asked to analyse and compare the way Shakespeare has portrayed the reactions of Macbeth and Lady Macbeth to the murder of King Duncan. For this I will be using act 2 scene 2 and act 1 scene 5 as well as quotes from other scenes in the play. I will start with analysis, first of Lady Macbeth. Lady Macbeth has always been cold and calculating in previous scenes. A good example of how Shakespeare portrayed Lady Macbeth's character is in act one scene five. Here I have quoted her speech from this scene - ...
kills Macbeth and Malcolm is hailed as the new king.

In both the case of Macbeth and the case of Lady Macbeth their guilt eventually killed them but in different ways. While Lady Macbeth was driven mad by her guilt and killed herself, Macbeth went on a killing frenzy from his guilt and was eventually killed by someone who was his friend in the beginning when he went too far.

In conclusion, while Macbeth and Lady Macbeth may have shown their reactions to Duncan's murder in totally different ways both of them got their comeuppance eventually.